★Using RSO

RSO dosing: start low, go slow

The single most important rule for taking Rick Simpson Oil — and a simple, week-by-week schedule for building up your dose safely.

Updated September 20266 min readBy the 2nd Star care team
Short answer

How do you dose RSO tincture?

Start with a single drop — 10 mg — taken about an hour before bed. Stay there for a few days, then increase by another drop every 2 to 3 days only if you feel comfortable. Most patients find their relief within a week or two and simply stay at that dose. The whole rule is start low, go slow. This tincture is a concentrate, so if 10 mg is more than you want in a single drop, you can dilute it with MCT oil to whatever strength suits you.

RSO tincture is potent, so the difference between "just right" and "way too much" is only a few drops. The good news: dosing it well isn't complicated. If you only remember one thing, remember to start small and move up slowly — you can always take more tomorrow.

Why "start low, go slow" matters

RSO tincture is far more concentrated than flower or light edibles, and it's usually high in THC. Even a small starting dose can contain enough active cannabinoids to provide noticeable effects. Taking too much won't harm you long-term — you cannot fatally overdose on cannabis — but it can leave you feeling uncomfortably high, dizzy, or anxious for a few hours. Starting low avoids that, and going slow lets your body build tolerance so you stay comfortable as your dose grows.

The one rule
Start with a 1-drop dose at night. Increase only every few days, only if the last dose felt fine. If a dose feels like too much, go back down — there is no prize for rushing.

What a dose actually looks like

With our tincture dropper, measuring your dose is exact and easy — 1 drop contains precisely 10 mg of active RSO.

Potency varies slightly from batch to batch, so check the label on your bottle for its exact strength.

This is a concentrate — you can dilute it

Our tincture is a concentrate, and 10 mg in a single drop is a real dose. Small mistakes add up fast: two drops is 20 mg, five drops is 50 mg. Count every drop out loud if it helps, take it deliberately, and never top off a dose you can't clearly remember taking.

If this is your first time using cannabis, we strongly recommend diluting your first doses. If you would rather move in smaller steps than 10 mg at a time, you can dilute the tincture yourself. All you need is MCT oil — the same carrier oil the tincture is already made with, sold at most grocery, health food, and drug stores. Pour the tincture and the MCT oil into a clean container, cap it, and shake or stir until it is evenly mixed. Diluting does not remove any medicine. It spreads the same amount of RSO across more drops, so a smaller dose becomes easy to measure.

Diluting 2nd Star RSO with MCT oil
You want each drop to beRSO : MCTMCT per 1 mL of RSOMCT for a full 30 mL bottleFinished amount
10 mgas it comesnonenone30 mL
5 mg1 : 11 mL30 mL60 mL
2.5 mg1 : 33 mL90 mL120 mL
1 mg1 : 99 mL270 mL300 mL

Our bottle holds 30 mL (1 oz). Diluted all the way down to 1 mg per drop, a full bottle becomes 300 mL — about ten times the volume you started with — so most patients dilute a little at a time instead of the whole bottle at once.

If you dilute, do these four things
Label the new container with the strength and the date. Shake it before every use, since oils settle. Write down the math you used. And keep it stored well out of reach of children and pets — a diluted bottle still holds every milligram the original did.

A simple week-by-week schedule

This is a gentle schedule for everyday symptom relief — pain, sleep, nausea, appetite. Move at your own pace. There's no deadline, and staying at a lower dose that works is completely fine.

1
Week 1 — find your floor

One drop (10 mg), about an hour before bed. Stay here for several nights and notice how you feel — how you sleep, how you wake up, whether symptoms ease.

2
Weeks 1–2 — climb gently

If the starting dose feels fine, add 1 more drop (10 mg) every 2 to 3 days. Many patients reach the relief they need somewhere in here — and just stop climbing.

3
Weeks 3–4 — settle in

Once symptoms are managed at a dose you tolerate well, hold steady. Some patients split it — a dose or two in the daytime, more at night. If a dose ever feels like too much, drop back to the last number of drops that felt right.

How to take it

Taken sublingually under the tongue, tincture onset begins within 15 to 45 minutes. If swallowed, it comes on gradually over one to two hours and lasts several hours. That slow build is exactly why you wait before taking more — give the first dose time to fully arrive.

If you feel too high or anxious

It happens, and it passes. Feeling anxious, dizzy, or too sedated is uncomfortable but not dangerous. It fades on its own with time. You cannot fatally overdose on cannabis.

A few things that help

People also ask

How much RSO tincture should I start with?

Start with a single drop (10 mg) taken about an hour before bed. Stay there for several days before increasing, so you learn how your body responds.

How do I increase my RSO tincture dose?

Go slow. Increase by 1 drop (10 mg) every 2 to 3 days, only if the current dose feels comfortable. Many patients reach effective relief and simply stay there.

What does a starting dose look like?

A single drop from the bottle's dropper, which equals 10 mg of active RSO. Tinctures make exact liquid measuring straightforward without the mess of syringes.

Can I dilute RSO tincture to make each drop weaker?

Yes. RSO tincture is a concentrate, and you can dilute it with plain MCT oil to any strength you like. Mixing 1 part tincture with 1 part MCT oil takes each drop from 10 mg to 5 mg; 1 part tincture to 3 parts MCT gives 2.5 mg per drop; 1 part to 9 parts gives 1 mg per drop. Shake well, and label the new container with its strength.

When is the best time to take RSO tincture?

Most patients start with a single drop about an hour before bed, since RSO is usually high in THC and can cause drowsiness. A small daytime dose can be added later once you know how it affects you.

What if I take too much?

If you feel too high, you took more drops than you needed. You cannot fatally overdose on cannabis — rest somewhere safe, hydrate, and reduce your next dose by a drop or two. The effects fade within a few hours.

How long until RSO tincture works?

Held under the tongue, effects can start in 15 to 45 minutes; swallowed directly, it builds over 1 to 2 hours and lasts several hours. Finding your comfortable dose usually takes a few weeks of small, gradual increases.

★

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2nd Star provides Medical Grade RSO — free of charge — to New Mexico patients, and we pair every supply with clear dosing guidance. Your request is private and reviewed by a real person.

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This guide is for education and is not medical advice. RSO is not a proven cure for any disease. Dosing varies from person to person — always talk with your doctor or care team before starting cannabis, especially if you are in treatment or take other medications.