Using RSO

RSO dosing: start low, go slow

The single most important rule for taking Rick Simpson Oil — and a simple, week-by-week schedule for building up your dose safely.

Updated June 20266 min readBy the 2nd Star care team
Short answer

How do you dose RSO?

Start with a dose about the size of a grain of rice — roughly 10 mg — taken about an hour before bed. Stay there for a few days, then increase by another rice grain every 3 to 4 days only if you feel comfortable. Most patients find their relief within a few weeks and simply stay at that dose. The whole rule is start low, go slow.

RSO is concentrated, so the difference between "just right" and "way too much" is tiny. The good news: dosing it well isn't complicated. If you only remember one thing, remember to start small and move up slowly — you can always take more tomorrow.

Why "start low, go slow" matters

RSO is far more concentrated than flower or most edibles, and it's usually high in THC. A dose the size of a grain of rice can contain as much active cannabinoid as several strong edibles. Taking too much won't harm you long-term — you cannot fatally overdose on cannabis — but it can leave you feeling uncomfortably high, dizzy, or anxious for a few hours. Starting low avoids that, and going slow lets your body build tolerance so you stay comfortable as your dose grows.

The one rule
Start with a rice-grain-sized dose at night. Increase only every few days, only if the last dose felt fine. If a dose feels like too much, go back down — there is no prize for rushing.

What a dose actually looks like

When people say "a grain of rice," they mean it literally — a small drop of thick oil about the size of a short grain of white rice. That's roughly 10 mg, or about a half to one notch on a dosing syringe.

A simple week-by-week schedule

This is a gentle schedule for everyday symptom relief — pain, sleep, nausea, appetite. Move at your own pace. There's no deadline, and staying at a lower dose that works is completely fine.

1
Week 1 — find your floor

One rice-grain dose (≈10 mg), about an hour before bed. Stay here for several nights and notice how you feel — how you sleep, how you wake up, whether symptoms ease.

2
Weeks 2–3 — climb gently

If the starting dose feels fine, add about one more rice grain every 3 to 4 days. Many patients reach the relief they need somewhere in here — and just stop climbing.

3
Weeks 4–5 — settle in

Once symptoms are managed at a dose you tolerate well, hold steady. Some patients split it — a little in the daytime, more at night. If a dose ever feels like too much, drop back to the last one that felt right.

About the 90-day "Rick Simpson protocol"
You may read about an intensive protocol that builds up to a gram of RSO a day over about 90 days. That's a much faster, higher-dose approach some people use during serious illness — and it should only be done with guidance from your care team. For most patients seeking symptom relief, the gentle schedule above is a better place to start.

How to take it

Taken by mouth, RSO comes on gradually over one to two hours and lasts several hours. That slow build is exactly why you wait before taking more — give the first dose time to fully arrive.

If you take too much

It happens, and it passes. If you feel too high — dizzy, anxious, too sedated — remember it isn't dangerous and it will fade on its own within a few hours.

A few things that help

People also ask

How much RSO should I start with?

Start with a dose about the size of a grain of rice — roughly 10 mg — taken about an hour before bed. Stay there for several days before increasing, so you learn how your body responds.

How do I increase my RSO dose?

Go slow. Increase by about one rice-grain-sized amount every 3 to 4 days, only if the current dose feels comfortable. Many patients reach effective relief and simply stay there.

What does a grain-of-rice dose look like?

A small drop of oil about the size of a short grain of white rice — roughly 10 mg, or a half to one notch on a dosing syringe. RSO is concentrated, so a little goes a long way.

When is the best time to take RSO?

Most patients start with a single dose about an hour before bed, since RSO is usually high in THC and can cause drowsiness. A small daytime dose can be added later once you know how it affects you.

What if I take too much?

If you feel too high, you took more than you needed. You cannot fatally overdose on cannabis — rest somewhere safe, hydrate, and reduce your next dose. The effects fade within a few hours.

How long until RSO works?

Taken by mouth, RSO builds over one to two hours and lasts several hours. Finding your comfortable dose usually takes a few weeks of small, gradual increases.

Free RSO, with guidance to match

2nd Star provides Medical Grade RSO — free of charge — to New Mexico patients, and we pair every supply with clear dosing guidance. Your request is private and reviewed by a real person.

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This guide is for education and is not medical advice. RSO is not a proven cure for any disease. Dosing varies from person to person — always talk with your doctor or care team before starting cannabis, especially if you are in treatment or take other medications.