Can I use RSO during cancer treatment?
Many patients do. RSO (Rick Simpson Oil) is a concentrated full-spectrum cannabis oil taken by mouth, and during chemotherapy and radiation it is used to ease nausea, pain, poor sleep, appetite loss, and anxiety. It is not a cure for cancer and is not a substitute for treatment. Because it can interact with common medications, tell your oncology team before you start, use a lab-tested product, and start with a very small dose.
Treatment is supposed to make you better, and it usually does — but the road there can be brutal. Nausea that makes food impossible. Pain that doesn't answer to pills. Nights spent awake, wondering. If you're in the middle of that, this guide is for you. It's a plain-language look at how RSO fits into cancer care: what it actually helps with, what it doesn't do, and how to use it without getting in the way of the treatment that matters most.
What treatment does to your body
Chemotherapy attacks fast-dividing cells — cancer cells, but also the lining of your stomach and mouth, your hair, and your bone marrow. Radiation inflames whatever it passes through. The result is the list most patients bring to us: nausea and vomiting, loss of appetite, pain (including chemo-induced nerve pain in the hands and feet), insomnia, and anxiety. Your oncology team has real tools for each of these, and you should use them. RSO is something many patients add on top, especially when standard anti-nausea drugs don't fully work.
What RSO is, briefly
RSO stands for Rick Simpson Oil — a thick, highly concentrated cannabis extract taken by mouth rather than smoked. It is full-spectrum, meaning it keeps the plant's natural mix of THC, CBD, and other compounds, which many believe work better together than alone. Because it's so concentrated, our tincture is dosed by the drop — a single drop is about 10 mg, and new users should dilute it further in plain MCT oil. For the full primer, read What is RSO?.
Cannabis for treatment side effects is not a fringe idea. The National Cancer Institute's clinician summary on cannabis and cannabinoids lists its potential benefits for people with cancer as anti-nausea effects, appetite stimulation, pain relief, and improved sleep — and notes that two THC-based prescription drugs, dronabinol and nabilone, are FDA-approved for chemotherapy side effects. The same summary is clear that the FDA has not approved cannabis to treat cancer itself.
What RSO can help with during treatment
Your body has a built-in network called the endocannabinoid system that helps regulate nausea, appetite, pain, sleep, and mood — almost exactly the list of things treatment disrupts. The compounds in RSO interact with that system. Here is what patients most often tell us it does for them:
- Calms nausea. A small dose before or after an infusion helps many people keep food and fluids down. See RSO for appetite loss & nausea.
- Brings appetite back. THC is well known for stimulating hunger. For a patient losing weight, that is medicine.
- Eases pain — including nerve pain from chemotherapy, which ordinary painkillers often miss. See RSO for chronic pain.
- Helps you sleep. A nighttime dose is where most patients start, and rest is when the body repairs. See RSO for sleep & insomnia.
- Softens anxiety. Many describe simply feeling less braced against the day.
- Reduces reliance on other drugs. Some patients find they need less of their anti-nausea or opioid medication. Only change prescribed medicines with your doctor.
What RSO cannot do
It cannot cure cancer. Laboratory and animal studies on cannabinoids and tumor cells are real but early, and the NCI notes that no clinical trials support cannabis as a cancer treatment in people. It cannot replace your treatment — patients who abandon proven therapy for cannabis oil lose time they may not get back. And it cannot fix everything at once: RSO builds gradually, sleep first, then appetite and nausea, then a steadier baseline over weeks.
Four rules for using RSO safely during treatment
What to expect in the first weeks
The first few nights, expect better sleep and not much else. Over the next couple of weeks, as the dose eases upward, most patients notice mornings with less nausea and a little more interest in food. Pain relief usually follows. Treatment cycles will still have hard days; RSO tends to make them shorter and shallower rather than erase them. The patients who do best are the ones who go slow, keep their team informed, and treat RSO as one tool among several.
Is RSO legal — and can I afford it?
In New Mexico, yes: cannabis is legal for adults 21 and over and for registered medical patients, and RSO is available through licensed channels. For a family already facing treatment costs, the real barrier is price. Quality RSO is expensive month after month, and making it at home is dangerous. That gap is exactly why 2nd Star exists.
How to get RSO free during cancer treatment in New Mexico
2nd Star is a New Mexico community project founded by a cancer survivor who used RSO through her own treatment. We provide Medical Grade RSO — free of charge — to qualifying New Mexico patients living with cancer and other serious illness, and we pair every supply with clear dosing guidance. "Medical Grade" means it's produced to a consistent, tested standard, not improvised at home.
If you or a family member is in treatment, you can make a request through our short, confidential intake form. There's no cost, no insurance, and no catch — free medical cannabis, reviewed by a real person.
Can I take RSO during chemotherapy?
Many patients do, to ease nausea, pain, poor sleep, and appetite loss during treatment. Because chemotherapy drugs and cannabis are both processed by the liver, tell your oncology team before you start so they can watch for interactions and adjust your care. Never stop or change a prescribed treatment to take RSO.
Does RSO cure cancer?
No. RSO is not a proven cure for cancer or any other disease. Claims online that it shrinks or eliminates tumors are not supported by clinical evidence in people. Patients use RSO for symptom relief alongside conventional treatment, not in place of it.
What does RSO help with during cancer treatment?
Patients most often use it for chemo-related nausea and vomiting, loss of appetite, pain (including nerve pain from chemotherapy), trouble sleeping, and anxiety. Many describe it as taking the edge off treatment so they can eat, rest, and get through the next round.
Can RSO interfere with chemo or radiation?
It can interact with medications, including blood thinners like warfarin, certain antidepressants, anti-rejection drugs, some chemotherapy agents, and sedatives, because they share the same liver enzymes. Radiation itself does not interact with cannabis, but the medications around it may. This is why your oncology team needs to know what you are taking.
How much RSO should a cancer patient take?
Start with a tiny fraction of a drop, about 2.5 to 5 mg of THC or a rice-grain-sized amount, at bedtime, and increase slowly over days and weeks. Older online protocols calling for 60 grams in 90 days can cause severe intoxication and anxiety; medical experts advise against them. A small nightly dose is often enough to sleep and wake with less nausea.
How can cancer patients get RSO for free in New Mexico?
2nd Star, a New Mexico community project, provides Medical Grade RSO at no cost to qualifying patients living with cancer and other serious illness. You can apply through the confidential intake form on this site. It is always free.
Treatment is hard enough
2nd Star provides Medical Grade RSO — free of charge — to New Mexico patients going through cancer treatment. Your request is private and reviewed by a real person.
Request free RSOThis guide is for education and is not medical advice. RSO is not a proven cure for cancer or any other disease. Always talk with your oncologist and care team before starting cannabis during treatment, especially if you take other medications.